Colinex Colistimethate Sodium 3 MIU

Colinex

Colistimethate Sodium 3 MIU

  • Loading dose of 9 MIU would achieve target concentration faster as compared to current dosing schedule
  • Without administration of loading dose, it takes 2-3 days to attain steady state concentration of Colistin.
  • Patients undergoing CRRT can be given high dose of CMS as it is continuously filtered and absorbed by dialysis membrane.
  • Nephrotoxicity is mostly mild and reversible. Serum creatinine level returned to normal after discontinuation of CMS therapy.